taking hydrochlorothiazide and furosemide together will casuse what kind of effect? will the 2 cause a blackout
emilymay8603 replied: "This is a great site to see what meds interact with other meds:
furosemide and hydrochlorothiazide (Moderate Drug-Drug)
MONITOR: The combination of a thiazide and loop diuretic may produce additive or synergistic effects on diuresis and excretion of electrolytes including sodium, potassium, magnesium, and chloride. Although these agents may be combined therapeutically in some patients with inadequate response to a single agent, the increased risk of dehydration, hypotension, hypokalemia, hypomagnesemia, and hyponatremia should be recognized. The exact mechanism of interaction is unclear but appears to be pharmacodynamic rather than pharmacokinetic.
MANAGEMENT: Caution is advised during concomitant use of a thiazide and loop diuretic. Dosages should be titrated slowly and carefully, and electrolytes, BUN, fluid status, blood pressure, and renal function should be monitored regularly. Patients should be advised to contact their physician if they experience signs and symptoms of fluid and electrolyte depletion such as dizziness, lightheadedness, dry mouth, thirst, fatigue, weakness, lethargy, muscle cramps, decreased urination, postural hypotension, and tachycardia."
K8 replied: "Taking both together should cause an increased diuretic effect, which means you will produce more urine.
However, using them together COULD cause you to black out due to either
1. Loss of too much fluid, or
2. Loss of too much electrolyte (losing too many natural body salts)."

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